Nexium, the brand name for esomeprazole, is a proton pump inhibitor (PPI) used for the treatment of gastroesophageal reflux disease (GERD). Its effectiveness has been demonstrated in clinical trials. These clinical trials included more than 2,500 patients with a history of heartburn and GERD. Esomeprazole is a PPI that works by blocking the production of acid in the stomach.
When taken as directed, esomeprazole reduces the amount of stomach acid produced by the kidneys, thereby reducing symptoms such as heartburn and acid reflux. It should be noted that esomeprazole is also known for its efficacy against proton pump inhibitors (PPIs) such as omeprazole and esomeprazole. While these PPIs are used for the treatment of gastroesophageal reflux disease (GERD), they are also prescribed off-label for the management of erosive esophagitis (damage to the stomach over time). Off-label use is where a patient is prescribed Nexium to treat conditions such as erosive esophagitis and Zollinger-Ellison syndrome.
Nexium is commonly prescribed to treat conditions such as heartburn, acid reflux, GERD, and erosive esophagitis. However, it can also be used to treat conditions such as erosive esophagitis and Zollinger-Ellison syndrome. The primary uses of Nexium for these conditions include:
Nexium is also available as a proton pump inhibitor (PPI). PPIs like esomeprazole work by blocking the production of acid in the stomach and reducing the amount of acid needed to heal the stomach. Esomeprazole reduces stomach acid production by blocking the action of an enzyme called H+/K+ ATPase, which helps to remove excess acid from the stomach and heal it.
Nexium (Esomeprazole) works by opening the communication lines between the stomach and the small intestine by preventing acid production. As a result, Nexium reduces the amount of acid in the stomach and reduces symptoms of GERD. Nexium is effective in treating conditions such as:
It is important to note that Nexium does not work against the development of cancer in the stomach or small intestine. Rather, it prevents it from growing and spreading the disease in those individuals who are at risk for developing cancer.
To determine the dosage of Nexium to treat conditions like Zollinger-Ellison syndrome, take the following dosage forms:
The initial dose of Nexium is 500 mg once daily. The dosage of esomeprazole may vary depending on the condition being treated. In clinical trials, most patients receiving esomeprazole had a dosage of esomeprazole 500 mg once daily for 14 consecutive days. In these clinical trials, patients typically received the medication for 7 to 10 days. If there is a delay between the start of and the start of treatment with esomeprazole, the patient should be given a full course of treatment for a maximum of 14 days. The recommended dosage range for patients receiving esomeprazole 500 mg once daily is from 1,000 mg to 2,000 mg per day.
Nexium is effective in reducing the symptoms of heartburn and acid reflux. The main effects of Nexium are:
While the primary effectiveness of Nexium for heartburn and acid reflux is in reducing symptoms, it can also be beneficial in managing the symptoms of GERD.
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Alternate Name:Pharmapure RX Esomep-EZS
Description:Nexium treats gastroesophageal reflux disease (GERD), esophagitis, and stomach ulcers. The generic version of Nexium is esomeprazole magnesium. For a supply of 30 oral tablets of Nexium Delayed-Release Capsules 40 mg is approximately $287. Take advantage of our LowerMyRx discount to receive a typical Nexium discount of up to 80% off of the retail price at participating pharmacies near you.
Dosage Form:Capsule Delayed Release
Administration Route:By mouth
Drug Class:Gastric Acid Secretion Inhibitor, Gastrointestinal Agent
Generic Available:Yes
Strength:20 MG
Warnings:Tell your doctor if you are pregnant or breastfeeding, or if you have kidney disease, liver disease, lupus, vitamin B12 deficiency, or osteoporosis. This medicine may cause the following problems: Kidney problems, including acute tubulointerstitial nephritisIncreased risk of broken bones in the hip, wrist, or spine (more likely if used several times per day or longer than 1 year)Serious skin reactions, including Stevens-Johnson syndrome, toxic epidermal necrolysis, acute generalized exanthematous pustulosis, and drug reaction with eosinophilia and systemic symptoms (DRESS)LupusFundic gland polyps (abnormal growth in the upper part of your stomach) This medicine can cause diarrhea. Call your doctor if the diarrhea becomes severe, does not stop, or is bloody. Do not take any medicine to stop diarrhea until you have talked to your doctor. Diarrhea can occur 2 months or more after you stop taking this medicine. Tell any doctor or dentist who treats you that you are using this medicine. This medicine may affect certain medical test results. Your doctor will do lab tests at regular visits to check on the effects of this medicine. Keep all appointments. Keep all medicine out of the reach of children. Never share your medicine with anyone. Stomach pain, nausea, vomiting, weight loss, bloody or black stools
Food Warnings:Do not use esomeprazole if you are also using medicines that contain rilpivirine., Some medicines can affect how esomeprazole works. Tell your doctor if you are using any of the following: Atazanavir, cilostazol, diazepam, digoxin, erlotinib, ketoconazole, methotrexate, mycophenolate mofetil, nelfinavir, rifampin, saquinavir, St John's wort, tacrolimus, voriconazoleBlood thinner (including clopidogrel or warfarin)Diuretic (water pill)Iron supplements, This medicine can cause diarrhea. Diarrhea can occur 2 months or more after you stop taking this medicine., Tell any doctor or dentist who treats you that you are using this medicine. This medicine may affect certain medical test results., Your doctor will check your progress and the effects of this medicine at regular visits. Keep all appointments., Keep all medicine out of the reach of children.
Applies to: NexiumEGD, Zollinger-Ellison syndrome
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Details
Nexium Control provides a course of treatment for relieving symptoms of heartburn, indigestion, and acid reflux. Each pack contains 7 tablets intended for short-term use. These tablets work by reducing stomach acid production, thereby managing discomfort associated with digestive acid-related conditions. It's important to follow the instructions provided for optimal results. GlaxoSmithKline (UK) Trading Limited GSK Consumer Healthcare (IE) Ltd., 980 Great West Road, Brentford, TW8 9GS, U. K. Or: 12 Riverwalk, Citywest Business Campus, Dublin 24, Ireland.
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Ingredients
Ingredients: Each Gastro-Resistant Tablet contains 20 mg Esomeprazole (as Magnesium Trihydrate). Contains sucrose. See package leaflet for further information. As we are always looking to improve our products, our formulations change from time to time, so please always check the packaging before use.
Directions
Directions for use: Take one tablet once a day. Do not exceed this dose. The tablets should be swallowed whole. Do not chew or crush the tablets. May take 2-3 days for full effect. If your symptoms worsen or do not improve after taking this medicine for 14 days in a row, contact your doctor. Read the package leaflet before use. Oral use. Storage recommendation: Do not store above 30°C. Store in the original package in order to protect from moisture. Keep out of the sight and reach of children.
utyrosanthoulosisreetings, I am sending this to my pharmacist friend in the pharmacy to see if it works. I have noticed that Nexium Control provides a full course of treatment. What I want to know is is the dosage would be the best choice. I have tried everything I could find for a 12-tablet pack, but they all come with the same results. So could you recommend the correct dosage to see results? I am not sure yet, but I would recommend taking it once a day and then trying it several times a week.What should I do if I am taking too much of Esomeprazole? I have read many people using this wonder drug are at risk of developing esomeprazole resistance. Can this be a side effect of Nexium?
I have read that taking too much of Esomeprazole can lead to gastrointestinal side effects, such as stomach pain and indigestion. Is Esomeprazole a safe or effective treatment for this condition?
The Protonix brand for Nexium Control provides a continuous course of treatment that provides symptomatic relief. If symptoms persist or worsen after taking this medicine for 14 days in a row, contact your doctor.
I am not a pharmacist, nor a doctor. I do not recommend taking esomeprazole if you are taking any form of acid reducer or proton pump inhibitor. Nexium Control provides a continuous course that provides symptomatic relief.